Our Clinical Trials
Clinical trials are an important aspect of our research and we have a very active roster. The Naomi Berrie Diabetes Center is the site for one of the country’s largest programs of clinical trials in Type 1 diabetes, particularly those involving children.
"Clinical trials benefit everyone."
Robin S. Goland, MD
Co-Founder and Co-Director
A clinical trial sets out to provide research scientists and doctors with answers to specific questions in a clinical setting. People who volunteer for clinical trials, or studies, play an indispensable role in helping find better ways to prevent, diagnose or treat diabetes.
Click here to support clinical trials at the Berrie Center.
An inside track to our clinical trials
Clinical trials are going on at the Berrie Center all the time. Here are some that are currently enrolling patients. Many patients enroll in trials when their doctors think they may benefit. Feel free to discuss a trial with your doctor if you (or your child) fit the description.
Click on the clinical trial for more information:
Noninvasive Imaging of Pancreatic Beta Cell Mass Using PET Scan
Purpose of Study
The goal of this study is to learn if we can image the pancreatic beta cell, the insulin-producing cell, by PET scanning.
Type of diabetes:
Subjects with type 1 diabetes, type 2 diabetes, healthy non-diabetic subjects
Age:
18-60 years
Time Commitment:
2 half days. The first visit is for a glucose tolerance test. The second visit is for a PET scan and CT scan of the abdomen.
Reimbursement:
$350 at completion of the PET and CT scans.
Contact:
Patricia Kringas, RN at (212) 851-5489 or email mpk40@columbia.edu
Oral Insulin Study
Purpose of Study
To determine whether a daily oral insulin capsule can prevent or delay type 1 diabetes in at-risk relatives of people with type 1 diabetes.
Time Commitment:
A blood test every 6 months.
Reimbursement:
Patients receive study drugs and glucose testing supplies at no cost during the study. Patients are also reimbursed for each visit.
Contact:
Ellen Greenberg, M.S. at (212) 851-5425 or email emg25@columbia.edu
Skin Biopsies for the Generation of Disease-Specific Embryonic Stem Cells
Purpose of Study
The aim of this study is to develop stem cell lines that have the characteristics of people with diabetes.
Type of diabetes:
Patients with type 1 diabetes or MODY
Age:
>1 year of age
Time Commitment:
Subjects will have a skin biopsy (1/8 inch in diameter) and a blood draw at a Berrie Center visit.
Reimbursement:
none
Contact:
Ellen Greenberg, M.S. at (212) 851-5425 or email emg25@columbia.edu
Study of Immune Function in Type 1 Diabetes: Subjects Wanted to Undergo Bone Marrow Aspiration
Purpose of Study
The aim of this study is to identify immune alterations that characterize type 1 diabetes.
Type of diabetes:
Subjects with type 1 diabetes and non-diabetic healthy subjects with no family history of diabetes are eligible.
Age:
18 and older
Time Commitment:
2 Berrie Center visits; 1 visit for blood draw and return visit for bone marrow aspirate.
Reimbursement:
$25 for visit 1 and $250 for visit including bone marrow aspirate.
Contact:
Ellen Greenberg, M.S. at (212) 851-5425 or email emg25@columbia.edu
Teplizumab (Anti-CD3) for Prevention of Type 1 Diabetes
Purpose of Study
To determine whether an investigational agent teplizumab (antiCD3) preserves insulin secretion and pancreatic beta cell function in subjects who have impaired glucose tolerance and are at high risk to develop type 1 diabetes. In this study, teplizumab is compared to a placebo.
Age:
16-45
Contact:
Ellen Greenberg, M.S. at (212) 851-5425 or email emg25@columbia.edu
TrialNet Type 1 Diabetes Pathway To Prevention Study
Purpose of Study
To screen relatives of type 1 diabetes for the antibodies associated with a higher risk of developing type 1 diabetes. Autoantibodies are a sign that the immune system may be attacking the insulin-producing cells in the pancreas. Click to view the related consent form and assent form.
Time Commitment:
One-time blood test.
Contact:
Ellen Greenberg, M.S. at (212) 851-5425 or email emg25@columbia.edu
Type 1 Diabetes Exchange
Purpose of Study
The T1D Exchange is an online patient registry that will collect information to improve diabetes management and accelerate research efforts.
Type of diabetes:
Patients with type 1 diabetes.
Age:
All ages
Reimbursement:
$20 for enrolling
Contact:
Ellen Greenberg, M.S. at (212) 851-5425 or email emg25@columbia.edu
Type 2 Diabetes Onset in Adolescence and Youth: Genetics Study
Purpose of Study
The aim of this study is to identify the genes responsible for adolescent-onset type 2 diabetes.
Age:
Any age; diabetes onset prior to age 18
Contact:
Patricia Kringas, RN at (212) 851-5489 or email mpk40@columbia.edu
